There are three locations in eDesk where you can set your signature
User signature: Each user has their own unique signature
Company signature: One single company-wide signature
Channel signature: A unique signature for each channel
You can use system snippets in the signature such as #agent_first_name# or #agent_full_name# to populate the sender’s name
01 User Signature
Account → Profile Preferences → Mailbox tab → User email signature
- Set your signature here to allow each user have their own unique signature
- This must be set by each user individually
- If using this option, you must enter #agent_signature# in the signature field in the channel settings (Settings → Channels → select the channel → Mailbox tab → Email signature)
02 Company Signature
Company Settings → Mailbox tab → Message signature
- Set your signature to have the same signature for every message sent from eDesk, regardless of the channel or user
- You can use the snippet #agent_first_name# or #agent_full_name# to have the agent’s name automatically pulled into the signature on each message
03 Channel Signature
Settings → Channels → select a channel → Mailbox tab 
- Set your signature here to have a specific one for each channel
- You can use the snippet #agent_first_name# or #agent_full_name# to have the agent’s name automatically pulled into the signature on each message
- If using this option, you must enter the snippet #channel_signature# in the company settings signature field (Settings → Company Settings → Mailbox tab → Message signature)